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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPB41L4B
All Species:
9.09
Human Site:
Y680
Identified Species:
16.67
UniProt:
Q9H329
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H329
NP_060894.2
900
99712
Y680
V
R
K
L
T
R
Q
Y
S
F
D
E
D
D
L
Chimpanzee
Pan troglodytes
XP_520178
925
103214
Y705
V
R
K
L
T
R
Q
Y
S
F
D
E
D
D
L
Rhesus Macaque
Macaca mulatta
XP_001102639
820
92159
D605
R
Q
Y
S
F
D
E
D
D
L
P
P
D
L
A
Dog
Lupus familis
XP_532028
914
101864
M699
V
E
T
T
Q
P
A
M
E
K
P
E
I
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMC8
527
59559
K312
I
G
L
F
F
W
P
K
I
T
K
M
D
F
K
Rat
Rattus norvegicus
B2RYE5
527
59553
K312
I
G
L
F
F
W
P
K
I
T
K
M
D
F
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509941
820
90648
N605
S
E
A
S
N
E
E
N
K
A
P
G
P
E
D
Chicken
Gallus gallus
XP_419046
839
94372
Y624
V
R
K
L
T
R
Q
Y
S
F
D
E
D
D
L
Frog
Xenopus laevis
NP_001080234
498
57093
L283
F
K
K
S
K
L
T
L
V
V
V
E
D
D
E
Zebra Danio
Brachydanio rerio
O57457
619
70690
K404
S
A
S
V
Q
Q
E
K
P
S
A
P
W
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650291
972
105216
K676
N
I
K
C
N
I
L
K
A
R
V
E
E
E
L
Honey Bee
Apis mellifera
XP_623974
809
90976
K594
A
K
S
L
E
Q
G
K
N
S
N
L
V
S
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788387
843
92835
P625
L
K
G
T
T
N
G
P
V
L
N
T
P
Y
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88
89.1
84.5
N.A.
54.6
54.6
N.A.
35.2
67.1
36.4
25.4
N.A.
33.9
35.3
N.A.
34.6
Protein Similarity:
100
89.8
90
86.9
N.A.
56.6
56.8
N.A.
47.7
75.3
45.4
40.7
N.A.
49.2
52
N.A.
50.1
P-Site Identity:
100
100
6.6
13.3
N.A.
6.6
6.6
N.A.
0
100
26.6
0
N.A.
20
6.6
N.A.
6.6
P-Site Similarity:
100
100
20
13.3
N.A.
13.3
13.3
N.A.
13.3
100
33.3
26.6
N.A.
40
40
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
0
0
8
0
8
8
8
0
0
0
8
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
8
8
0
24
0
54
31
8
% D
% Glu:
0
16
0
0
8
8
24
0
8
0
0
47
8
24
16
% E
% Phe:
8
0
0
16
24
0
0
0
0
24
0
0
0
16
0
% F
% Gly:
0
16
8
0
0
0
16
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
16
8
0
0
0
8
0
0
16
0
0
0
8
0
8
% I
% Lys:
0
24
39
0
8
0
0
39
8
8
16
0
0
8
16
% K
% Leu:
8
0
16
31
0
8
8
8
0
16
0
8
0
8
31
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
16
0
0
0
% M
% Asn:
8
0
0
0
16
8
0
8
8
0
16
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
16
8
8
0
24
16
16
0
8
% P
% Gln:
0
8
0
0
16
16
24
0
0
0
0
0
0
0
8
% Q
% Arg:
8
24
0
0
0
24
0
0
0
8
0
0
0
0
0
% R
% Ser:
16
0
16
24
0
0
0
0
24
16
0
0
0
8
0
% S
% Thr:
0
0
8
16
31
0
8
0
0
16
0
8
0
0
0
% T
% Val:
31
0
0
8
0
0
0
0
16
8
16
0
8
0
0
% V
% Trp:
0
0
0
0
0
16
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
8
0
0
0
0
24
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _